From Milano Centrale train to Spiez, train to Interlaken Ost, then train to Grindelwald. 4hrs 02min SFr 73. From via orefici p.za cordusio bus to Milan Lampugnano, bus to Bellinzona, Stazione, line 191 bus to Airolo, Stazione, then drive to Grindelwald. 6hrs 45min SFr 75. From Milan drive to Grindelwald. 3hrs 30min SFr 59.