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From Second and Jefferson line 20 bus to Memphis, TN, bus to Nashville, TN, then bus to Louisville, KY. 9hrs 22min $66. From Memphis drive to Louisville. 6hrs 16min $48. From Second and Jefferson line 20 bus to Memphis airport, fly to Louisville airport, then line 2 bus to Louisville. 7hrs 08min $223. From Second and Jefferson line 20 bus to Memphis airport, fly to Covington airport, taxi to Cincinnati, OH, then bus to Louisville. 6hrs 58min $312.

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