From Manchester Airport train to Wilmslow, train to Shrewsbury, then train to Aberystwyth. 3hrs 57min £35. From Manchester Airport The Station bus to Manchester City Centre, Manchester Central Coach Station, line 385 bus to Bangor, Bus Station (Bangor Bus Station), then bus to Aberystwyth, Park Avenue. 7hrs 34min £42. From Manchester drive to Aberystwyth. 3hrs 08min £26.