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From Madrid Puerta del Sol train to Madrid-Chamartin, train to Ávila, bus to Aveiro, train to Coimbra-B, then train to Coimbra. 7hrs 45min 67 €. From Madrid Puerta del Sol train to Madrid-Chamartin, train to Coimbra-B, then train to Coimbra. 32hrs 38min 48 €. From Madrid drive to Coimbra. 5hrs 48min 86 €. From Recoletos train to Madrid airport, fly to Porto airport, Metro to Porto(Campanha), then train to Coimbra. 5hrs 32min 64 €. From Recoletos train to Madrid airport, fly to Lisbon airport, Metro to Lisboa Oriente, then train to Coimbra. 6hrs 05min 79 €.