From London Heathrow airport fly to Manchester airport then train to Crewe. 2hrs 12min $105. From London Heathrow airport fly to Leeds Bradford airport, line 757 bus to Leeds, train to Manchester Piccadilly, then train to Crewe. 3hrs 18min $131. From Heathrow Terminal 1 train to Paddington Underground Station, Tube to London Euston, then train to Crewe. 2hrs 08min $93. From Heathrow Central Bus Station bus to Oxford City Centre, Carfax (Stop I2), bus to Oxford, train to Stoke-on-Trent Railway Station, then line 3 bus to Crewe, Bus Station. 5hrs 42min $92. From London Heathrow drive to Crewe. 2hrs 47min $57.