From London Heathrow airport fly to Manchester airport then train to Crewe. 3hrs 12min $105. From London Heathrow airport fly to Leeds Bradford airport, line 757 bus to Leeds, train to Manchester Piccadilly, then train to Crewe. 4hrs 18min $131. From Heathrow Terminal 1 train to Paddington Underground Station, Tube to London Euston, then train to Crewe. 2hrs 01min $93. From Heathrow Central Bus Station line 230 bus to Brook Furlong, Milton Keynes Coachway (Milton Keynes Coachway Car Park), bus to Milton Keynes Centr., then train to Crewe. 2hrs 58min $65. From London Heathrow drive to Crewe. 2hrs 47min $57.