From London Heathrow airport fly to Manchester airport then train to Crewe. 3hrs 12min $105. From London Heathrow airport fly to Leeds Bradford airport, line 757 bus to Leeds, train to Manchester Piccadilly, then train to Crewe. 4hrs 21min $131. From Heathrow Terminal 1 train to Paddington (H&C Line)-Underground, Tube to London Euston, then train to Crewe. 2hrs 09min $94. From Heathrow Central Bus Station line 230 bus to Brook Furlong, Milton Keynes Coachway (Milton Keynes Coachway Car Park), bus to Milton Keynes Centr., then train to Crewe. 3hrs 02min $66. From Heathrow Central Bus Station bus to Gloucester Green Bus Station, bus to Digbeth, Birmingham Coach Station NatExpress, bus to Hanley, Bus Station (stand N), then line 20 bus to Crewe, Bus Station. 7hrs 03min $73. From London Heathrow drive to Crewe. 2hrs 47min $60.