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From Lecce train to Via Bastioni San Giorgia, bus to Brindisi airport, fly to Palermo airport, then train to Palermo. 7hrs 18min 133€. From Lecce train to Bari Centrale, train to Bari airport, fly to Palermo airport, then train to Palermo. 6hrs 11min 112€. From Lecce train to Via Bastioni San Giorgia, bus to Brindisi airport, fly to Trapani airport, then bus to Palermo. 9hrs 56min 216€. From Lecce train to Via Bastioni San Giorgia, bus to Brindisi airport, fly to Catania airport, then bus to Palermo. 9hrs 20min 164€. From Lecce bus to Messina FS then bus to Palermo. 11hrs 16min 48€. From Lecce train to Brindisi, train to Taranto, train to Sibari, train to Castiglione Cosentino, train to Paola, train to Villa San Giovanni, ferry to Messina Centrale, then train to Palermo Centrale. 14hrs 19min 119€. From Lecce line 350 Bus to Taranto then bus to Palermo Centrale. 14hrs 23min 42€. From Lecce drive to Villa San Giovanni, Car ferry to Rada San Francesco, then drive to Palermo. 8hrs 38min 135€.

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