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From Lecce bus to Catania FS then bus to Palermo. 12hrs 20min 49 €. From Lecce train to Brindisi, train to Taranto, train to Sibari, train to Castiglione Cosentino, train to Paola, train to Villa San Giovanni, ferry to Messina Centrale, then train to Palermo Centrale. 13hrs 28min 120 €. From Lecce line 350 bus to Taranto then bus to Palermo Centrale. 14hrs 23min 48 €. From Lecce drive to Villa San Giovanni, Car ferry to Rada San Francesco, then drive to Palermo. 8hrs 38min 131 €. From Lecce line 793 bus to Brindisi airport, fly to Palermo airport, then train to Palermo. 8hrs 21min 123 €. From Lecce train to Bari Centrale, train to Bari airport, fly to Palermo airport, then train to Palermo. 6hrs 44min 113 €. From Lecce line 793 bus to Brindisi airport, fly to Trapani airport, then bus to Palermo. 11hrs 00min 203 €. From Lecce line 793 bus to Brindisi airport, fly to Catania airport, then bus to Palermo. 10hrs 24min 156 €.

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