From Genova Brignole train to Pisa Centrale then train to Firenze S.M.N.. 3hrs 07min 29€. From Genova bus to Florence. 3hrs 57min 25€. From Gênes rideshare to Florence. 3hrs 06min 13€. From Genoa drive to Florence. 2hrs 36min 44€. From Genova Piazza Principe train to Genoa airport, fly to Florence airport, then bus to Florence. 5hrs 59min 155€.