From Genova Brignole train to Pisa Centrale then train to Firenze S.M.N.. 3hrs 06min 43€. From Genova bus to Florence. 3hrs 57min 30€. From Gênes rideshare to Florence. 2hrs 27min 14€. From Genoa drive to Florence. 2hrs 36min 44€. From Genova Piazza Principe train to Genoa airport, fly to Florence airport, then train to Florence. 5hrs 52min 150€.