From Euston, Barnham Road line 332 bus to Bury St Edmunds, train to Cambridge, train to London Euston, then train to Chester. 5hrs 32min £62. From Euston, Barnham Road line 332 bus to Bury St Edmunds, Bus Station, line 305 bus to Digbeth, Birmingham Coach Station NatExpress, then line 304 bus to Chester, Bus Exchange. 9hrs 32min £37. From Euston drive to Chester. 3hrs 37min £46.