From Canary Wharf Underground Station Tube to Baker Street Underground Station, Tube to London Paddington, then train to Slough. 1hrs 05min £12. From Canary Wharf bus to Mile End Underground Station, Tube to Ealing Broadway, then train to Slough. 1hrs 31min £12. From Poplar, Canada Square South bus to Victoria then bus to Slough Bus Station. 2hrs 14min £7. From Canary Wharf bus to Charing Cross, Trafalgar Square, bus to Hounslow Bus Station, then line 81 bus to Slough Bus Station. 2hrs 29min £6. From Canary Wharf taxi to Slough. 45min £127. From Canary Wharf drive to Slough. 45min £6.