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From Busko-Zdrój bus to Tarnów, Bus to Florence, bus to Perugia Station, then bus to Assisi. 32hrs 58min. From Busko-Zdrój drive to Assisi. 17hrs 05min. From Busko-Zdrój bus to Kielce, train to Krakow Glowny, train to Krakow Mydlniki Wap., taxi to Krakow airport, fly to Rome airport, train to Roma Termini, train to Foligno, then bus to Assisi. 14hrs 07min. From Busko-Zdrój bus to Kielce, train to Krakow Glowny, train to Krakow Mydlniki Wap., taxi to Krakow airport, fly to Rome Ciampino airport, train to Roma Termini, train to Foligno, then bus to Assisi. 13hrs 29min. From Busko-Zdrój bus to Kielce, train to Krakow Glowny, train to Krakow Mydlniki Wap., taxi to Krakow airport, fly to Bologna airport, Aerobus to Bologna Centrale, train to Firenze S.M.N., train to Bastia Umbra, then bus to Assisi. 15hrs 24min. From Busko-Zdrój bus to Kielce, train to Katowice station, bus to Katowice airport, fly to Rome Ciampino airport, train to Roma Termini, train to Foligno, then bus to Assisi. 15hrs 25min. From Busko-Zdrój bus to Kielce, train to Krakow Glowny, train to Krakow Mydlniki Wap., taxi to Krakow airport, fly to Pisa airport, train to Firenze S.M.N., train to Bastia Umbra, then bus to Assisi. 15hrs 19min.